计算机应用 ›› 2014, Vol. 34 ›› Issue (12): 3599-3604.

• 虚拟现实与数字媒体 • 上一篇    下一篇

CT图像肺结节的毛刺检测与量化评估

邢谦谦1,刘哲星1,林炳权2,钱俊1,曹蕾1   

  1. 1. 南方医科大学 生物医学工程学院,广州 510515
    2. 南方医院 影像中心,广州 510515
  • 收稿日期:2014-06-09 修回日期:2014-07-23 出版日期:2014-12-01 发布日期:2014-12-31
  • 通讯作者: 邢谦谦
  • 作者简介:邢谦谦(1989-),女,山东济南人,硕士研究生,主要研究方向:医学图像处理;刘哲星(1972-),男,山西太原人,副教授,主要研究方向:医学图像处理;林炳权(1983-),男,广东汕头人,博士,主要研究方向:CT影像诊断;钱俊(1975-),女,安徽歙县人,副教授,主要研究方向:生物统计;曹蕾(1974-),女,湖南沅江人,副教授,主要研究方向:医学图像处理、软件工程。
  • 基金资助:

    国家自然科学基金青年基金资助项目;国家自然科学基金资助项目;广东省教育部产学研项目

Detection and quantitative evaluation of lung nodule spiculation in CT images

XING Qiamqiam1,LIU Zhexing1,LIN Binquan2,QIAN Jun1,CAO Lei1   

  1. 1. School of Biomedical Engineering, Southern Medical University, Guangzhou Guangdong 510515, China;
    2. Image Center, Nanfang Hospital, Guangzhou Guangdong 510515, China
  • Received:2014-06-09 Revised:2014-07-23 Online:2014-12-01 Published:2014-12-31
  • Contact: XING Qiamqiam

摘要:

为准确检测并量化评估毛刺征,提出一种CT图像肺结节的毛刺检测与量化评估方法。首先利用区域生长算法与水平集方法结合进行结节主体的准确分割;而后利用线性滤波模板提取结节主体周边区域的毛刺;最后引入毛刺水平指数作为毛刺特征的量化指标。在此基础上对结节有无毛刺进行分类,并与肺部图像数据库联盟(LIDC)的量化评级进行一致性和相关性分析。实验结果表明,该方法可以有效地检测并定量描述CT图像肺结节的毛刺征。

Abstract:

A new method was proposed to accurately detect and quantitatively evaluate the lung nodule spiculation. First, the region growing method followed by level set method was used to accurately segment the main part of the lung nodule. Then, spiculated lines connected to the nodule boundary were extracted using a line detector in polar coordinates system. Finally, spiculation index was introduced as the quantitative measurement of spiculation features, which was then used as a criteria for distinguishing between spiculated and non-spiculated nodules. The consistency and correlation of spiculation index of the method and Lung Image Database Consortium (LIDC) were evaluated in detail. The experimental results show that the proposed method can effectively detect and quantitatively describe the lung nodule spiculation in CT images.

中图分类号: