计算机应用 ›› 2019, Vol. 39 ›› Issue (4): 963-971.DOI: 10.11772/j.issn.1001-9081.2018081850

• 人工智能 • 上一篇    下一篇

正常衰老的人脑功能网络演化模型

丁超, 赵海, 司帅宗, 朱剑   

  1. 东北大学 计算机科学与工程学院, 沈阳 110819
  • 收稿日期:2018-09-05 修回日期:2018-10-03 发布日期:2019-04-10 出版日期:2019-04-10
  • 通讯作者: 丁超
  • 作者简介:丁超(1993-),男,安徽合肥人,硕士研究生,主要研究方向:脑功能网络构建与分析;赵海(1959-),男,辽宁沈阳人,教授,博士,主要研究方向:网络科学、互联网生命特征、无线传感器网络、物联网、体域网;司帅宗(1987-),男,河南濮阳人,博士研究生,主要研究方向:复杂系统、复杂网络;朱剑(1981-),男,江苏扬中人,讲师,博士,主要研究方向:复杂系统。
  • 基金资助:
    中央高校基本科研业务费专项资金资助项目(N161608001,N171903002)。

Evolution model of normal aging human brain functional network

DING Chao, ZHAO Hai, SI Shuaizong, ZHU Jian   

  1. School of Computer Science and Engineering, Northeastern University, Shenyang Liaoning 110819, China
  • Received:2018-09-05 Revised:2018-10-03 Online:2019-04-10 Published:2019-04-10
  • Supported by:
    This work is partially supported by the Fundamental Research Funds for the Central Universities (N161608001, N171903002).

摘要: 为了对正常衰老的人脑功能网络(NABFN)的拓扑结构变化进行探究,提出一种基于朴素贝叶斯的网络演化模型(NBM)。首先,依据朴素贝叶斯(NB)的链路预测算法与解剖距离来定义节点间存在连边的概率;其次,利用特定的网络演化算法,在青年人的脑功能网络基础上,通过不断地增加连边来逐步得到相应中年及老年时期的模拟网络;最后,为了对模拟网络与真实网络间的相似程度进行评价,提出网络相似指标(SI)值。仿真实验结果表明,与基于共同邻居的网络演化模型(CNM)相比,NBM构建的模拟网络与真实网络间的SI值(4.479 4,3.402 1)高于CNM模拟网络对应的SI值(4.100 4,3.013 2);并且,两者模拟网络的SI值均明显高于随机网络演化算法所得模拟网络的SI值(1.892 0,1.591 2)。实验结果证实NBM能够更为准确地预测出NABFN的拓扑结构变化过程。

关键词: 脑功能网络, 演化模型, 演化算法, 链路预测, 朴素贝叶斯

Abstract: In order to explore the topological changes of Normal Aging human Brain Functional Network (NABFN), a network evolution Model based on Naive Bayes (NBM) was proposed. Firstly, the probability of existing edges between nodes was defined based on link prediction algorithm of Naive Bayes (NB) and anatomical distance. Secondly, based on the brain functional networks of young people, a specific network evolution algorithm was used to obtain a simulation network of the corresponding middle-aged and old-aged gradually by constantly adding edges. Finally, a network Similarity Index (SI) was proposed to evaluate the similarity degree between the simulation network and the real network. In the comparison experiments with network evolution Model based on Common Neighbor (CNM), the SI values between the simulation networks constructed by NBM and the real networks (4.479 4, 3.402 1) are higher than those of CNM (4.100 4, 3.013 2). Moreover, the SI value of both simulation networks are significantly higher than those of simulation networks derived from random network evolution algorithm (1.892 0, 1.591 2). The experimental results confirm that NBM can predict the topological changing process of NABFN more accurately.

Key words: brain functional network, evolution model, evolution algorithm, link prediction, Naive Bayes (NB)

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