Journal of Computer Applications ›› 2019, Vol. 39 ›› Issue (4): 1196-1200.DOI: 10.11772/j.issn.1001-9081.2018081823

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Fractional differential algorithm based on wavelet transform applied on texture enhancement of liver tumor in CT image

QIU Jiajun1, WU Yue1, HUI Bei2, LIU Yanbo2   

  1. 1. School of Computer Science and Engineering, University of Electronic Science and Technology of China, Chengdu Sichuan 611731, China;
    2. School of Information and Software Engineering, University of Electronic Science and Technology of China, Chengdu Sichuan 610054, China
  • Received:2018-09-04 Revised:2018-10-15 Online:2019-04-10 Published:2019-04-10
  • Supported by:
    This work is partially supported by the Fundamental Research Funds for the Central Universities (ZYGX2016J092).

基于小波变换的分数阶微分算法在肝脏肿瘤CT图像纹理增强中的应用

邱甲军1, 吴跃1, 惠孛2, 刘彦伯2   

  1. 1. 电子科技大学 计算机科学与工程学院, 成都 611731;
    2. 电子科技大学 信息与软件工程学院, 成都 610054
  • 通讯作者: 吴跃
  • 作者简介:邱甲军(1984-),男,湖南涟源人,博士研究生,主要研究方向:医学图像处理;吴跃(1958-),男,四川成都人,教授,硕士,博士生导师,主要研究方向:数据挖掘、网络计算;惠孛(1978-),男,四川成都人,副教授,博士,主要研究方向:机器学习;刘彦伯(1994-),男,北京人,硕士研究生,主要研究方向:医学图像处理。
  • 基金资助:
    中央高校基本科研业务费专项资金资助项目(ZYGX2016J092)。

Abstract: Smooth texture details are easily lost in the process of image texture enhancement. Although fractional-order differential enhancement can preserve the texture details of smooth regions nonlinearly, it is sensitive to frequency resolution. Focusing on this problem, a fractional differential texture enhancement algorithm based on wavelet transform was proposed and applied to texture enhancement of liver tumor regions in plain Computed Tomography (CT) images. Firstly, wavelet transform was used to decompose the image region of interest into multiple subband components. Then, a fractional differential mask with compensation parameter was constructed based on fractional-order differential definition. Finally, the mask was used to convolve with each high frequency subband component respectively, and the image region of interest was recombined by using reverse wavelet transform. The experimental results show that the algorithm effectively preserves the low-frequency smooth texture details while observably enhances the high-frequency contour information of the tumor region by a relatively large fractional order:compared with the original region, the enhanced hepatocellular carcinoma region has the information entropy increased by 36.56% averagely, the average gradient increased by 321.56% averagely, and the mean absolute difference of 9.287 averagely; compared with the original region, the enhanced hepatic hemangioma region has the information entropy increased by 48.77% averagely, the average gradient increased by 511.26% averagely, and the mean absolute difference of 14.097 averagely.

Key words: texture enhancement, wavelet transform, fractional differential, hepatocellular carcinoma, hepatic hemangioma, Computed Tomography (CT) image

摘要: 图像纹理增强过程中容易丢失平滑区域纹理细节,而分数阶微分增强虽然能够非线性保留平滑区域纹理细节,但对频率分辨率敏感。针对这个问题,提出一种基于小波变换的分数阶微分纹理增强算法,应用于平扫计算机断层扫描(CT)图像的肝脏肿瘤区域的纹理增强。首先,通过小波变换将图像感兴趣区分解成多个子带分量;其次,基于分数阶微分定义构造一个带补偿参数的分数阶微分掩膜;最后,使用该掩膜与每个高频子带分量进行卷积并利用小波逆变换重组图像感兴趣区。实验结果表明,该方法在使用较大分数阶次显著增强肿瘤区域的高频轮廓信息的同时,有效地保留了低频平滑的纹理细节:增强后的肝细胞癌区域与原区域相比,信息熵平均增加36.56%,平均梯度平均增加321.56%,平均绝对差值平均为9.287;增强后的肝血管瘤区域与原区域相比,信息熵平均增加48.77%,平均梯度平均增加511.26%,平均绝对差值平均为14.097。

关键词: 纹理增强, 小波变换, 分数阶微分, 肝细胞癌, 肝血管瘤, 计算机断层扫描图像

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