Aiming at the photo spoofing problem that often occurs in identity verification, a face liveness detection model based on InceptionV3 and feature fusion, called InceptionV3 and Feature Fusion (InceptionV3_FF), was proposed. Firstly, the InceptionV3 model was pretrained on ImageNet dataset. Secondly, the shallow, middle, and deep features of the image were obtained from different layers of the InceptionV3 model. Thirdly, different features were fused to obtain the final features. Finally, the fully connected layer was used to classify the features to achieve end-to-end training. The InceptionV3_FF model was simulated on NUAA dataset and self-made STAR dataset. Experimental results show that the proposed InceptionV3_FF model achieves the accuracy of 99.96% and 98.85% on NUAA dataset and STAR dataset respectively, which are higher than those of the InceptionV3 transfer learning and transfer fine-tuning models. Compared with Nonlinear Diffusion-CNN (ND-CNN), Diffusion Kernel (DK), Heterogeneous Kernel-Convolutional Neural Network (HK-CNN) and other models, the InceptionV3_FF model has higher accuracy on NUAA dataset and has certain advantages. When the InceptionV3_FF model recognizes a single image randomly selected from the dataset, it only takes 4 ms. The face liveness detection system consisted of the InceptionV3_FF model and OpenCV can identify real and fake faces.