When multiple agents performing path finding in large-scale warehousing environment, the existing algorithms have problems that agents are prone to fall into congestion areas and it take a long time. In response to the above problem, an improved Conflict-Based Search (CBS) algorithm was proposed. Firstly, the existing single warehousing environment modeling method was optimized. Based on the traditional grid based modeling, which is easy to solve path conflicts, a hybrid modeling method of grid-heat map was proposed, and congestion areas in the warehouse were located through a heat map, thereby addressing the issue of multiple agents prone to falling into congestion areas. Then, an improved CBS algorithm was employed to solve the Multi-Agent Path Finding (MAPF) problems in large-scale warehousing environment. Finally, a Heat Map for Explicit Estimation Conflict-Based Search (HM-EECBS) algorithm was proposed. Experimental results show that on warehouse-20-40-10-2-2 large map set, when the number of agents is 500, compared with Explicit Estimation Conflict-Based Search (EECBS) algorithm and Lazy Constraints Addition for MAPF (LaCAM) algorithm, HM-EECBS algorithm has the solution time reduced by about 88% and 73% respectively; when there is 5%,10% area congestion in warehouse, the success rate of HM-EECBS algorithm is increased by about 49% and 20% respectively, which illustrates that the proposed algorithm is suitable for solving MAPF problems in large-scale and congested warehousing and logistics environments.