At present， researches on SQLite encryption both domestically and internationally are conducted at the file level and with the single-key， resulting in coarse encryption granularity and low decryption difficulty. In response to the security shortcomings of SQLite， a multi-key page-level encryption system was proposed. Firstly， an independent page key was assigned to each physical page， allowing for individual encryption and decryption of each page. A key file was introduced to store all page keys. Secondly， a page key cache module KeyCache was designed to generate and cache page keys for pages， thereby reducing the performance loss caused by frequent I/O read and write operations. Thirdly， an encryption and decryption module Crypto was proposed to implement the encryption and decryption functions. Crypto was used to quickly retrieve page keys through KeyCache， consequently enhancing the overall system performance. A comparative experiment was conducted between the proposed system and typical SQLCipher. Experimental results show that in read and update tests， compared with SQLCipher， the execution time of the proposed system reduced by 1.5% and 3.0% on average， achieving better performance at a higher security level. Additionally， in create and delete tests， the proposed system exhibits minimal performance loss compared to SQLCipher and the performance loss is close to SQLCipher while significantly enhancing the security level， verifying the effectiveness of the proposed system.