Abstract: Abstract: Since the energy consumption of the nodes in WSN is excessively high, the transmission delay is too long, and data integrity is poor, A routing algorithm based on multiple mobile sink nodes considering Qos is proposed. Firstly, The density of the nodes is determined by the strength of the signal received from the base station. And the WSN is Divided into autonomous areas according to the K-means theory. Secondly, a mobile sink is assigned to each autonomous area, and the trajectory of the mobile sink node is determined by using the SVR. Finally, the depth and queue potential field is introduced to transmit data packets with high sensitivity and high data integrity through Improved-IDDR algorithm. Theoretical analysis and simulation results show that compared with GLRM algorithm and LEACH algorithm, the energy consumption of routing strategy is decreased 21.2% and 23.7%; and the end-to-end delay of the algorithm is decreased by 15.23% and 17.93%; the data integrity is better. Experimental results show that MSTSDG can effectively improve the performance of the system in real networks.